Differential effects of ICN1 expression on αβ versus γδ T-cell development from human pro-T (TN1) and pre-T (TN3) cells. Cell numbers for the indicated subsets derived from ICN1- or mock-transduced CD34^hi pro-T cell precursors (TN1) and CD4 ISP T-committed pre-T cells (TN3) were determined after 20 to 30 days in a hu/mo FTOC assay. Absolute numbers were calculated as the mean ± SD of at least 14 samples from 3 to 4 independent experiments. Numbers were normalized to 2 × 10³ GFP⁺ transduced cells/lobe.