p210 BCR/ABL kinase affects the sensitivity to UVC cytotoxicity. (A) BaF3 and BaF3-p210 lymphoid cells and (B) 32D and 32D-p210 myeloid cells were pretreated or not with 1 μM STI571 for 24 hours and irradiated with the indicated dose of UVC. Cell viability was assessed 48 hours later using trypan blue exclusion test (left panels). Cell growth was tested in clonogenic assay (right panels). Each experiment was performed in duplicate, and the results are represented as a mean ± SD of 3 separate experiments. The * and ** indicate difference between values for p210 BCR/ABL-positive and -negative cells at P < .05 and P < .01, respectively, as determined by Student t test.