Comparison of SF-36 profile. Measured at the baseline for each dimension with other profiles in healthy men from the general Italian population (•, thin solid line; n = 999), patients with diabetes (▴, dotted line; n = 98), and patients on dialysis (♦, dashed line; n = 87).³⁸  •, thick line indicates COCIS (n = 50). ^*Significant difference (P < .05), as computed by Student t test, between our hemophilia patients with inhibitors and the Italian male population. ^**Italian patients with diabetes and on dialysis. ○ indicates Italian patients with diabetes; PF, physical functioning; BP, bodily pain; RP, role-physical; GH, general health; VT, energy/vitality; RE, role-emotional; SF, social functioning; and MH, mental health.