Slight time-dependent increase in pentose cycle activity relative to glycolysis in TRMA cells with or without thiamine treatment. Pentose cycle activity relative to the Embden-Meyerhoff-Parnas pathway is shown here by the m₁/m₂ ratios in lactate. Pentose cycle activity showed a modest time-dependent increase in both thiamine-depleted and thiamine-replete TRMA cultures. (Mean ± SD; n = 9).