Figure 3.
Figure 3. Aberrant collagen and convulxin-induced aggregation in GP VInull mice. Blood was withdrawn from GP VIWT, GP VIhet, and GP VInull mice. Mouse platelet-rich plasma was obtained by pooling blood from animals with the same genotype. The platelet number in each sample was normalized to 240 × 109/L with platelet-poor plasma. Indicated concentrations of acid-insoluble fibrillar collagen (type I), convulxin, and PMA were added to stirred platelets and the aggregation profiles are presented.

Aberrant collagen and convulxin-induced aggregation in GP VInull mice. Blood was withdrawn from GP VIWT, GP VIhet, and GP VInull mice. Mouse platelet-rich plasma was obtained by pooling blood from animals with the same genotype. The platelet number in each sample was normalized to 240 × 109/L with platelet-poor plasma. Indicated concentrations of acid-insoluble fibrillar collagen (type I), convulxin, and PMA were added to stirred platelets and the aggregation profiles are presented.

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