Figure 4.
Figure 4. Reversion of BALB-neuT BM hyperplasia after transplantation into normal mice. BM from 23- to 28-week-old BALB-neuT females bearing 4 to 10 tumors was transplanted into 9-week-old CB6F1 mice. (A) Kinetics of BM uptake and reversion of myeloid hyperplasia in PB of mice with transplants. (B) CFU assay in spleen cells of 21-week-old CB6F1 mice with transplants (12 weeks after transplantation). (C) Proliferation of total splenocytes from CB6F1 (□) and control (▪) mice with transplants in response to alloantigens in mixed leukocyte reaction. Results shown are from 3 of 6 mice tested. Mean of 3 replicates ± SD.

Reversion of BALB-neuT BM hyperplasia after transplantation into normal mice. BM from 23- to 28-week-old BALB-neuT females bearing 4 to 10 tumors was transplanted into 9-week-old CB6F1 mice. (A) Kinetics of BM uptake and reversion of myeloid hyperplasia in PB of mice with transplants. (B) CFU assay in spleen cells of 21-week-old CB6F1 mice with transplants (12 weeks after transplantation). (C) Proliferation of total splenocytes from CB6F1 (□) and control (▪) mice with transplants in response to alloantigens in mixed leukocyte reaction. Results shown are from 3 of 6 mice tested. Mean of 3 replicates ± SD.

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