CHS response induced by TNCB. (A) CHS response was induced by TNCB in TNCB-sensitized β4GalT-I^+/– (□;n = 11) and β4GalT-I^–/– (▦; n = 11) mice. Ear swelling was calculated as described in “Materials and methods.” (B) MPO activity in the CHS-induced earlobe. TNCB-sensitized or nonsensitized β4GalT-I^+/– (□) and β4GalT-I^–/– (▦) mice were treated with TNCB, and the MPO activity in the earlobe homogenates was measured. Data are presented as means ± SEM.