Neutrophil trafficking during acute inflammation. (A) Zymosan-induced dermatitis. Earlobes of β4GalT-I^+/– (□; n = 8) and β4GalT-I^–/– (▦; n = 10) mice were injected subcutaneously with zymosan (right ear) or saline (left ear), and the weight of each earlobe disk was measured after 8 hours. Ear swelling was calculated as described in “Materials and methods.” (B) MPO activity in the earlobe homogenates was measured. Data are presented as means ± SEM.