PMA-induced FucT-VII expression is inhibited by MAPK inhibitors. JSB3 cells were stimulated with 1 nM PMA in the presence or absence of the indicated concentrations of PD98059, SB203580, MerckC, alone or in combination, and expression of FucT-VII was assessed by HECA-452 staining. (A) Representative histograms of PMA-treated JSB3 cells with no inhibitor, 50 μM PD98059, 50 μM SB203580, or both compounds. (B) Quantitative analysis of the effect of all inhibitors for all experiments (n = 19). Results are depicted as the mean ± SEM percent HECA-452⁺.*P < .05 versus treatment with PMA with no inhibitors; **P < .05 versus groups with a single asterisk (*).