Figure 1.
![Figure 1. B-cell proliferation in response to anti-RP105 or LPS stimulation. Spleen B cells (1 × 105/well) from wild-type and MyD88–/– mice (A) and wild-type and CD19–/– mice (B-C) were cultured with the indicated concentrations of anti-RP105 Abs (A-B) or LPS (C). Proliferation was assessed by the incorporation of labeled thymidine (1 μCi/well [0.037 MBq/well]) added during the last 16 hours of 72-hour cultures. Values represent the mean counts per minute (cpm; ± SEM) obtained from triplicate cultures. Mean values significantly different from wild-type proliferation levels are indicated, **P < .01. Results represent those obtained in 3 independent experiments.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/102/4/10.1182_blood-2002-11-3573/6/h81634769001.jpeg?Expires=1724239234&Signature=QU0KL7ZsJRTw8S9cn6mQNIiAkq2p3VBTkx-MR80BJcgfhhPWkKDmlDyPHm9umhKPMA8j~aWzqKR7wnJSoIsBk8o6kHd1aPG3K~hAF5YAXHMrxNY6Iu6u6eBVgAX~vKkvLSsfdUFnk2dg9yeX~CFimVpvVOlsvZENfX9qzPX0544ACTIiQSftzMA2DtyDzi8jPnsAdw7MFbB3RuViRfxNzlmnWFIwCTA7e4ZrK-B1R-fvpMtfVIW00vK-xLLUgDbTH1IuCfMoUswOKzGYyg49HOXkfpYGBu86vzYDP55yNQTiuWzcHXJ3O1em8181oaskykaWdTl-fKm1~C4qQ8ouHw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
B-cell proliferation in response to anti-RP105 or LPS stimulation. Spleen B cells (1 × 105/well) from wild-type and MyD88–/– mice (A) and wild-type and CD19–/– mice (B-C) were cultured with the indicated concentrations of anti-RP105 Abs (A-B) or LPS (C). Proliferation was assessed by the incorporation of labeled thymidine (1 μCi/well [0.037 MBq/well]) added during the last 16 hours of 72-hour cultures. Values represent the mean counts per minute (cpm; ± SEM) obtained from triplicate cultures. Mean values significantly different from wild-type proliferation levels are indicated, **P < .01. Results represent those obtained in 3 independent experiments.
