Parameters influencing overall survival. Age (A), karyotype (B), FAB subtype (C), white blood cell (WBC) count (D), and performance status (not shown) were the 5 main prognostic parameters influencing survival in univariate analysis (Table 6). Both karyotype and WBC remained significant in multivariate analysis of the whole population of patients. Only karyotype was a significant prognostic parameter when excluding transplantation (not shown).