Effect of resveratrol on procaspase 3 and PARP cleavage. OCIM2 cells were incubated with increasing concentrations of resveratrol for 18 hours. Levels of procaspase 3, caspase 3, and uncleaved and cleaved PARP proteins were detected by Western immunoblotting. The results shown here demonstrate dose-dependent decreases in levels of procaspase 3 and PARP and increases in cleaved caspase 3 and cleaved PARP.