PMNs fromPGRP-S^-/- mice are defective in generating oxidative burst in response to B subtilis andM luteus. Oxidative burst in blood PMNs from PGRP-S^+/+ (light gray bars) or PGRP-S^-/- (dark gray bars) mice in response to the indicated stimuli was measured by the NBT test. The results are means of 6 experiments, and the significance of differences was calculated using the Student t test.