Figure 4.
Effect of MPA treatment on purine nucleotide pools. 32D cells were treated with MPA at 2 μM for the indicated times. GTP (A) and ATP (B) levels were measured by HPLC. Data are from 1 representative experiment. Similar results were obtained in at least 3 other independent assays. The decrease in ATP following MPA treatment was also confirmed by luciferase assays.