Effect of anti–CTLA-4 immunotoxins on apoptosis induction of AML cells.

Percentage of viable neoplastic cells from an adult AML leukemia treated for 72 hours with scalar doses of 2 immunotoxins (83-Sap and 67-Sap), or a mixture of saporin and scFv (83+Sap and 67+Sap). Results are expressed as means of 3 different experiments. SD never exceeded 10%.