The transportation of HLA-DR is blocked in HCMV-infected cells. Confocal microscopy analysis was performed to examine the distribution of HLA-DR in HCMV, RVAD65-infected, and mock-infected cells at 1 day after infection. The staining pattern of HLA-DR is shown in panel A. Colocalization studies of HLA-DR (red) with LAMP-1 (green), rab 7 (green), or calreticulin (green) in uninfected and HCMV-infected cells is shown in panels B, C, and D, respectively. Original magnification, × 40.