Distribution of the normal and mutant CNO proteins in stably transfected fibroblasts. C57Bl/6J fibroblasts were transfected with pCMV-Tag4 FLAG expressing the normal (A-B) and mutant (C-D) CNO proteins and stained with anti-FLAG antibody. No disruption of the overall distribution of the mutant CNO protein is discernable. Original magnification × 1000.