Figure 4.
Figure 4. Individual follow-up data on estimates of myocardial iron concentration and urinary iron excretion collected during iron chelation in 14 patients with transfusional iron overload. Each patient is given identification number, route of administration, dose of DFO, and number of blood units received at start of treatment. ○ indicates urinary iron; □, myocardial iron. The horizontal line represents the upper limit of reference range (5.7 μmol/g). Arrows indicate start of vitamin C supplementation. * indicates increase of DFO dose to 1.5 g twice daily in patient 12. Clinical patient data are given in Table 1. Broad, horizontal bars reflect periods of time off DFO treatment. The iron excretion follow-up was not performed in patients 7, 12, and 14, and was incomplete in patients 4 and 13.

Individual follow-up data on estimates of myocardial iron concentration and urinary iron excretion collected during iron chelation in 14 patients with transfusional iron overload. Each patient is given identification number, route of administration, dose of DFO, and number of blood units received at start of treatment. ○ indicates urinary iron; □, myocardial iron. The horizontal line represents the upper limit of reference range (5.7 μmol/g). Arrows indicate start of vitamin C supplementation. * indicates increase of DFO dose to 1.5 g twice daily in patient 12. Clinical patient data are given in Table 1. Broad, horizontal bars reflect periods of time off DFO treatment. The iron excretion follow-up was not performed in patients 7, 12, and 14, and was incomplete in patients 4 and 13.

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