Relationship between indices of iron status and myocardial iron estimates. The relationships between liver iron concentration, urinary iron excretion, serum ferritin concentration, and the myocardial iron estimates were examined by linear regression analysis in 14 patients with transfusional iron overload investigated by MRI at start (A-C), after 3 months (D-F), and after 6 months (G-I) of DFO treatment. Variation in number of examinations in the panels is due to absent (patient 12) or incomplete (patients 7 and 14) urinary iron determination and incomplete MRI follow-up in patients 8 and 9. For details, see “Patients, materials, and methods.” Diagonal lines indicate linear regression lines.