Fig. 4.
Effect of intact 5H2 and its fragments on platelet aggregation induced by low concentrations of ADP.
Platelets were incubated for 4 minutes at 37°C with 5H2 (75 μg/mL), its F(ab′)2 (50 μg/mL) or Fab′ fragments (50 μg/mL), or buffer and then stimulated with a subthreshold concentration of ADP (1.10 μM) causing by itself only a first wave of aggregation. Tracings representative of 4 different experiments are shown.
