Cytotoxic activity of NK-92-scFv(FRP5)-ζ against ErbB2-expressing cancer cell lines.

Human SKBR3 (A) and T47D (C) breast carcinoma cells, SKOV3 ovarian carcinoma cells (B), and A431 squamous cell carcinoma cells (D) were incubated with NK-92-scFv(FRP5)-ζ (○) or parental NK-92 cells (●) at different E/T ratios for 2 hours. Specific lysis was determined in europium-release assays as described in the legend of Figure2.