Phenotypic analysis of CD8 T cells that stain with HIV, EBV, and CMV tetramers in 35 HIV-infected patients and 9 healthy donors.

Data are represented by dot plots depicting median (white bar) and interquartile distances (25th-75th percentiles, indicated by box). Dotted lines represent 1.5 interquartile distances. Any outlying data points outside the dotted lines are shown. Median values for each set of samples are given above the graphs. The statistical analysis of these data by 2-sided Wilcoxon rank sum test were tabulated and are indicated in Table3. Only a minority of tetramer-positive cells stained for perforin in most samples. There were no significant differences in perforin staining between HIV-specific and CMV- or EBV-specific cells in HIV-seropositive or healthy donors. However, differences in expression of the other markers are significant.