Symbolic analysis of the kinetics of clonal and multiclonal repopulation kinetics.

Secondary (A) and tertiary (B) transplants. Data depicted in Figures 3and 4 were analyzed as detailed in “Materials and methods.” Open symbols represent the Hamming distances for all comparisons of all repopulation curves derived from daughter HSCs with a clone or for daughter HSCs derived from multiclonal grafts. Mean Hamming distances (± SE) for clonal and multiclonal grafts are indicated as bars. These were 0.7 ± 0.08 for multiclonal, 0.2 ± 0.07 for clonal secondary grafts, and 0.7 ± 0.15 for multiclonal, 0.2 ± 0.17 for clonal tertiary grafts, respectively.