Fig. 3.
Iron measurements in wild-type and Hfemutant mice of different ages.
(A) Transferrin saturation was determined in 5-, 11-, and 22-week-old mice. (B) Liver iron was measured in 5-, 11-, and 22-week-old mice. (C) Five-, 11-, and 22-week-old mice were administered 59Fe by gavage and percentage administered iron absorbed was determined as described in “Materials and methods.” Open bars show results for wild-type mice (+/+); black bars, Hfe knockout mice (−/−; shaded bars, C282Y knockin (Y/Y). Error bars represent SEM. The number of animals in each group is shown above columns.
