Fig. 6.
Fig. 6. Survival probabilities. / Survival probabilities from the date of diagnosis among patients in the following genetic categories: 17p− (17p deletion regardless ofVH mutation status), 11q− (11q deletion and no 17p deletion, regardless of VH mutation status), unmutated VH (VH homology 97% or greater or 98% or greater and no 17p or 11q deletion), and mutated VH (VH homology less than 97% or less than 98% and no 17p or 11q deletion). Median survival times for the respective genetic subgroups were as follows: A (all patients and 97% VH homology cut-off): 17p− 30 months, 11q− 70 months, VH 97% or greater 89 months, and VH less than 97% not reached (58% survival at 152 months). B (Binet stage A patients and 97% VH homology cut-off): 17p− 36 months, 11q− 68 months, VH 97% or greater 82 months, and VH less than 97% not reached (55% survival at 152 months). C (all patients and 98% VHhomology cut-off): 17p− 30 months, 11q− 70 months,VH 98% or greater 89 months, andVH less than 98% not reached (54% survival at 152 months). D (Binet stage A patients and 98%VH homology cut-off): 17p− 36 months, 11q− 68 months, VH 98% or greater 86 months, andVH less than 98% not reached (52% survival at 152 months).

Survival probabilities.

Survival probabilities from the date of diagnosis among patients in the following genetic categories: 17p− (17p deletion regardless ofVH mutation status), 11q− (11q deletion and no 17p deletion, regardless of VH mutation status), unmutated VH (VH homology 97% or greater or 98% or greater and no 17p or 11q deletion), and mutated VH (VH homology less than 97% or less than 98% and no 17p or 11q deletion). Median survival times for the respective genetic subgroups were as follows: A (all patients and 97% VH homology cut-off): 17p− 30 months, 11q− 70 months, VH 97% or greater 89 months, and VH less than 97% not reached (58% survival at 152 months). B (Binet stage A patients and 97% VH homology cut-off): 17p− 36 months, 11q− 68 months, VH 97% or greater 82 months, and VH less than 97% not reached (55% survival at 152 months). C (all patients and 98% VHhomology cut-off): 17p− 30 months, 11q− 70 months,VH 98% or greater 89 months, andVH less than 98% not reached (54% survival at 152 months). D (Binet stage A patients and 98%VH homology cut-off): 17p− 36 months, 11q− 68 months, VH 98% or greater 86 months, andVH less than 98% not reached (52% survival at 152 months).

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