Examples of CD38 expression patterns.

The proportion of CLL cells expressing CD38 varied widely in the patient cohort studied (see also Figure 5). Three representative types of CD38 expression patterns of the CD19⁺/CD5⁺cell population of individual patients are shown. (A) Homogeneously positive (97.5% CD38⁺ cells). (B) Homogeneously negative (1.5% CD38⁺ cells). (C) Mixed expression pattern with CD38⁺ and CD38⁻ CLL cells (28.9% CD38+ cells).