Schematic representation of human Fas cDNAs structure.

The coding regions are represented as boxes; hatched, signal sequence (SP); dark shaded, transmembrane (TM) region; cross-hatched, signal transducing domain (ST); white boxes, sequences corresponding to the Fas protein; white boxes labeled A, B, and C correspond to sequences generated by a different reading frame. The nomenclature used to describe the variant Fas cDNAs corresponds to terminology proposed previously.25