Fig. 5.
Relationship between p53 dysfunction, CD38 expression, and IgVH mutation.

Relationship between p53 dysfunction, CD38 expression, and IgVH mutation.

(A) 2-D plot. Patients with functionally intact p53 are represented by open diamonds, those with type A p53 dysfunction by closed squares, and those with type B p53 dysfunction by closed triangles. Lines have been drawn to indicate the cutoff values used to define CLL subgroups on the basis of IgVH mutation and CD38 expression. (B) Venn diagram showing the relationship.

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