Fig. 3.
![Fig. 3. Cell susceptibility to denileukin diftitox by protein synthesis inhibition. / HUT78 cells (A), Sezary cells (B), and B-CLL cells (C) were exposed to10−10 M and 10−8 M alitretinoin (Panretin) (1) or bexarotene (2) for 48 hours. The cells were incubated with denileukin diftitox (Ontak) at various concentration for 72 hours. Inhibition of protein synthesis was measured by [14C]-leucine incorporation. All the data represent percent of counts per minute ± SEM of cells pulsed with [14C]-leucine.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/100/4/10.1182_blood-2002-01-0300/6/h81622990003.jpeg?Expires=1722418807&Signature=3QYYIum2Kaey6SvEw9daELqTpW-r3n~bBT8LNTFu8NSHZUXtzjb31bxP8Xfl5yVc~CR~1d-t5XfTPIcDQiY3R45xjYhwhX-Wj5xIuI7LU6nFT1UmlX8HK1tGohIo-Wmu200lJiMlzvpdhTPKJNzMxrwZfFsgRAkHNSx-BtDuv23fqHpokOcqRlvHTsp32V4fuTx3JycCuLrseMt770T0AXe~gJ6nKlOqxFdjWeW-hOapPFrC9S0lDS8lnyuUpBnaMDVYslwV0k6VvOSdgFmkEJMeLGVO3szkr2ejgEV0R-m848h8kk8o20E5yL4znGGY7P0wOr~3wf7ZA0ggpXFdjw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Cell susceptibility to denileukin diftitox by protein synthesis inhibition.
HUT78 cells (A), Sezary cells (B), and B-CLL cells (C) were exposed to10−10 M and 10−8 M alitretinoin (Panretin) (1) or bexarotene (2) for 48 hours. The cells were incubated with denileukin diftitox (Ontak) at various concentration for 72 hours. Inhibition of protein synthesis was measured by [14C]-leucine incorporation. All the data represent percent of counts per minute ± SEM of cells pulsed with [14C]-leucine.
