Fig. 7.
Azurophil granule exocytosis by mAb24-positive PMN.
(A) PMNs were incubated with neuroblastoma cells alone (control), GM-CSF alone, hu14.18 with or without GM-CSF, hu14.18/GM-CSF, or hu14.18/GM-CSF with anti-CD32, anti-CD16, or anti-CD11b for 5 to 120 minutes. (A) In this example, the expression of CD63 and the β2-integrin activation epitope (mAb24+) was evaluated at 60 minutes. (B) mAb24+CD63+cells per 10 000 events at 5 to 120 minutes were quantified. Data are from 1 of 3 experiments that provided similar results.
