Spreading and adhesion of PMN onto tumor cells and cytolysis with hu14.18 and hu14.18/GM-CSF.

PMNs (200 000) were incubated with LA-N-1 neuroblastoma cells (10 000) alone (control) for (A) 30 minutes and (B) 120 minutes; with hu14.18 (mAb) for (C) 30 minutes and (D) 120 minutes; or with hu14.18/GM-CSF (IC) for (E) 30 minutes and (F) 120 minutes. Electron micrographs were taken with an original magnification of × 5400.