Fig. 6.
Effect of AT III on LPS-induced secretion of IL-6 and TNF-α.
Monocytes were preincubated with AT III for 2 hours, as indicated, and then stimulated with 10 μg/mL LPS for 8 hours. IL-6 (A) and TNF-α (B) protein levels from cell supernatants were measured by ELISA. Values represent means ± SEM of 3 independent experiments, with assays performed in duplicate. *P < .01 versus stimulation in the absence of AT III.
