Fig. 3.
Fig. 3. MLL-AF10immortalized cells are leukemogenic. / (A) May-Grünwald/Giemsa–stained cells from peripheral blood show hyperleukocytosis with myeloblasts (× 50). (B) BM aspirate shows monotonous population of mononuclear cells (hematoxylin and eosin stain, × 10). (C) Liver displays extensive infiltration by blasts (hematoxylin and eosin stain, × 10; insert, × 20). (D) Fluorescence-activated cell sorter analysis of leukemia cells shows that most cells coexpress the surface antigens Mac1 and c-kit.

MLL-AF10immortalized cells are leukemogenic.

(A) May-Grünwald/Giemsa–stained cells from peripheral blood show hyperleukocytosis with myeloblasts (× 50). (B) BM aspirate shows monotonous population of mononuclear cells (hematoxylin and eosin stain, × 10). (C) Liver displays extensive infiltration by blasts (hematoxylin and eosin stain, × 10; insert, × 20). (D) Fluorescence-activated cell sorter analysis of leukemia cells shows that most cells coexpress the surface antigens Mac1 and c-kit.

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