Effect of the P2Y12 receptor antagonist, AR-C66096, on agonist-induced platelet aggregation.

The platelet aggregation induced by varying concentrations of (A) SFLLRN, (B) AYPGKF, or (C) thrombin in the absence (solid line) or presence (broken line) of 1 μM AR-C66096 was measured as described in “Materials and methods.” The data (mean ± SE) are obtained from at least 3 independent experiments using platelets from different donors.