Predictive value of an increase in DDAB titer for thrombocytopenia.

The 108 PPPs from patients of a phase IIB study of roxifiban who did not develop thrombocytopenia were analyzed by the DDAB ELISA at multiple time points prior to and during dosing. The first day of dosing is indicated (day 0). Note that the DDAB titers are relatively constant during the 30 days of dosing.