Alignments of important motifs for 9 proteins identified in hematopoietic stem cells.

(A) Clone 1317 with 3 closely related WEE1 kinase protein family members, which play an important role in mitosis. (B) Clone 1508 with 5 closely related members of the Zinc-finger protein CNBP DNA-binding family, which play a role in gene transcription. (C) Clone 2265 with 6 GLI protein family members, all of which are Zinc-finger DNA-binding proteins. (D) Clone 1405 with 2 C–ETA type protein kinases. (E) Clone 1797 with 5 closed relative insulin/IGF/relaxin family members, which play a role in insulin expression and distribution. (F) Clone 2131 with 6 GPR1/FUN34/yaaH family members. (G) Clone 2995 with a region of homology to MEKK1 proteins. (H) (I) Regions of similarity between 2 clones (3001 and 2858) and the Jak3 protein.