Increased apoptosis in MDS as measured by annexin V.

(A) Representative example of annexin V analysis showing greater annexin V level in a bone marrow sample in a patient with MDS than in a patient with AML. (B) Box plot showing significantly greater levels of annexin V expression in MDS patients than in AML patients. (C) Box blot showing significantly greater apoptotic activity in CD34⁺ cells from patients with MDS than in those from patients with AML. (D) Box blot showing significantly greater apoptotic activity in CD34⁺ cells from patients with various subtypes of MDS than in those from patients with AML.