Fig. 1.
IL-21 induced DNA synthesis in IL-6–dependent human myeloma cell lines.
Cell lines IH-1, OH-2, and ANBL-6 were stimulated with IL-21 and IL-6 in concentrations as indicated for 72 hours, and cell lines U-266, JJN-3, and RMPI 8226 were stimulated with IL-21 in the same manner. DNA synthesis was measured by 3H-thymidine incorporation. Data shown are representative of at least 2 different experiments, and error bars represent ± 1 SD of triplicate data.
