Depletion of CD25⁺ cells from whole spleen results in an acceleration of GVHD mortality.

Lethally irradiated B10.BR mice were recipients of B6 BM and either 15 × 10⁶ whole spleen or CD25-depleted spleen. On the x-axis are days after transfer of cells. On the y-axis is the proportion of recipients surviving (n = 8/group;P = .055).