Depletion of CD4⁺CD25⁺ cells accelerates GVHD lethality.

The 10⁵ (A) or 50 000 (B) whole CD4⁺ or CD25-depleted CD4⁺ B6 T cells were transferred into sublethally irradiated bm12 recipients. On the x-axis are days after transfer of cells. On the y-axis is the proportion of recipients surviving (n = 8/group; P = .024 for panel A;P = .0068 for panel B).