Serologic responses of the vaccinated mice to CD20⁺ cells.

(A) Staining of Raji cells with B1 anti-CD20 monoclonal antibody compared with isotype control (shaded). (B) Binding of mouse serum from a huCD20-KLH–vaccinated mouse compared with serum from a control mouse vaccinated with P190-KLH (shaded). Both sera were diluted 1:10. (C) Binding of B1 compared with isotype control. (D) Binding of serum from a mouse vaccinated with huCD20-avidin at 1:10 dilution and from a mouse vaccinated with avidin only (shaded).