Fig. 4.
Western blot analysis of PML-RARα cleavage in NB4 and R4 cells treated by tRA combined with HMBA or NaB.
The cells were treated with 10−7 μM tRA, 2 mM HMBA, and 0.5 mM NaB, alone or in combination as labeled, for 3 days. Anti-RARα antibody was used to detect PML-RARα and ΔPML-RARα.
