Mouse and human ferritin H genes.

In the murine gene, regulatory regions reside between 4 kb and 5 kb distal to the transcriptional start site; in the human gene, regulatory regions are just 5′ of the TATA box. However, similar sequence motifs and binding proteins suggest similar functional regulation of these genes. IF1 has not been definitively identified as binding to the G-fer region of the human ferritin H gene.115 See text for further explanation.