Fig. 1.
Fig. 1. Identification of Met680Ile (2040 G>C) mutation. / (A) A 391-bp PCR fragment was digested with NlaIII. The normal allele is cut to 320-, 46-, and 25-bp fragments, whereas the mutation (which leads to a loss of a NlaIII site) results in 366- and 25-bp fragments. (B) This was confirmed by automated sequencing.

Identification of Met680Ile (2040 G>C) mutation.

(A) A 391-bp PCR fragment was digested with NlaIII. The normal allele is cut to 320-, 46-, and 25-bp fragments, whereas the mutation (which leads to a loss of a NlaIII site) results in 366- and 25-bp fragments. (B) This was confirmed by automated sequencing.

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