Fig. 4.
Analysis of cell viability and apoptosis following Bcl-2, Bcl-xL, or Mcl-1 ASO delivery in the presence of Dex.
Cells were electroporated with either Bcl-2, Bcl-xL, or Mcl-1 ASO, or the mismatched related control. Then cells were resuspended in RPMI 1640 with 2% FCS in the presence or not of Dex (10−6 M). A control involving cells electroporated without ASO was performed. (A) Cell viability was determined as indicated in Figure 2. (B) The percentage of APO 2.7–positive cells was determined by flow cytometry. Results are expressed as the mean ± SD of 3 experiments.
