American Society of Hematology

Fig. 2.

$Fig. 2. Comparison of FPA, FPB, and factor XIII activation. / Clot time from all experiments was calculated to be 4.7 ± 0.2 minutes. Data are shown as the mean ± SEM. FPA (⋄) and FPB (●) release (24 and 9 experiments, respectively) are shown as μM versus time (minute). FPA release occurs prior to FPB release and occurs at 2.5 ± 0.7 minutes with a rate of propagation of 2.7 ± 0.2 μM/min. FPB release occurs at 2.8 ± 0.8 minutes with a rate of propagation of 1.2 ± 0.1 μM/min. Maximum FPB release is about 39% compared to FPA release. Factor XIII activation (▴) is shown as a relative fraction of activated factor XIII present at each time point, determined from densitometric analysis. Factor XIII activation occurs prior to FPA release at 2.5 ± 0.7 minutes and increases at a rate of 11.4% ± 1.0%/min.$

Comparison of FPA, FPB, and factor XIII activation.

Clot time from all experiments was calculated to be 4.7 ± 0.2 minutes. Data are shown as the mean ± SEM. FPA (⋄) and FPB (●) release (24 and 9 experiments, respectively) are shown as μM versus time (minute). FPA release occurs prior to FPB release and occurs at 2.5 ± 0.7 minutes with a rate of propagation of 2.7 ± 0.2 μM/min. FPB release occurs at 2.8 ± 0.8 minutes with a rate of propagation of 1.2 ± 0.1 μM/min. Maximum FPB release is about 39% compared to FPA release. Factor XIII activation (▴) is shown as a relative fraction of activated factor XIII present at each time point, determined from densitometric analysis. Factor XIII activation occurs prior to FPA release at 2.5 ± 0.7 minutes and increases at a rate of 11.4% ± 1.0%/min.

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