TCR-Vβ CDR3 size distribution analysis of expanded Vβ families in AA.

Two representative examples (patients AA1 and AA 2) are shown (of 20 performed). Columns represent percentages of lymphocytes belonging to a particular Vβ family as indicated on the x-axis. For overexpanded families, the results of the Vβ CDR3 size distribution analysis are depicted below each panel. For the spectrograms, the x-axis represents size of the PCR amplification product fragments as determined using fluorescent sequencing technique.