Flow cytometric analysis of the TCR-Vβ usage in AA patients.

For controls (n = 9; A,D,G,J), columns and bars represent mean + 2 SD of percentages of lymphocytes belonging to a particular Vβ family as indicated on the x-axis. The values are calculated as percentages of total αβ CD4⁺ (A,B,C) or CD8⁺ (G,H,I) lymphocytes. Similarly, contribution of individual Vβ families is represented as percentage of total αβ CD4⁺CD28^dim (D,E,F) and αβ CD8⁺CD28^dim (J,K,L) lymphocytes. For AA (B,E,H,K) and PNH patients (C,F,I,L), 2 representative cases (of a total of 33 studied) are shown.