Liver histology and VWF staining in AOM-induced FHF.

(A) Paraffin section AOM-50 mouse liver stained with hematoxylin and eosin and visualized by light microscopy. White arrows denote liver sinusoidal endothelial cells. Severe necrosis is identified by the bolded arrow. (B) Frozen section of AOM-50 mouse liver revealing staining of VWF in large vessel and sinusoidal endothelium by FITC immunofluorescence. Original magnification × 200 in panels A and B.