Expression of chemokine receptors by human NKT cells in circulation.

(A) Phenotype and frequency (n = 33) of human NKT cells examined in this study. (B) Chemokine receptor expression by Vα24⁺Vβ11⁺ NKT cells, CD4 (naive CD45RA⁺ and memory CD45RA⁻), and CD8 (naive CD45RA⁺CD27⁺, memory CD45RA⁻CD27⁺, and effector CD45RA⁺CD27⁻) T-cell subsets. Different symbols represent data from different donors, and horizontal bars represent averages (NKT cells, the upper left panel). Results from 6 donors (NKT cells) or averages ± SD from 4 donors (CD4 and CD8 T-cell subsets) are shown. (C) Chemokine receptor expression by Vα24⁺ Vβ11⁺ NKT cells shown as dot plots. Percentages positive are shown in parentheses.